09:00 - 09:40 Plenary Lecture (Chair: Hartmut Oschkinat)

Kurt Wüthrich (Zürich/San Diego)
NMR in structural and functional genomics

09:40 - 10:40 Membrane Proteins (Chair: Kurt Wüthrich)

09:40 - 10:00
Lars-Oliver Essen (Marburg, Germany)
Halorhodopsin: Light-driven ion pumping made simple?

10:00 - 10:20
Timothy A. Cross (Tallahassee, FL, USA)
Integral membrane proteins structural genomics: Mycobacterium tuberculosis

10:20 - 10:40
César Fernández Estrabao (Zürich, Switzerland)
Solution NMR structure of the E. coli outer membrane protein OmpX

10:40 - 11:10 Coffee Break

11:10 - 11:50 Plenary Lecture (Chair: Ivano Bertini)

Chris Sander (Cambridge, USA)
The challenge of structural genomics

11:50 - 12:50 Structural Genomics and Disease (Chair: Ian A. Wilson)

11:50 - 12:10
Wim Hol (Seattle, WA, USA)
Medicinal protein crystallography and structural genomics for tropical diseases

12:10 - 12:30
Duncan McRee (San Diego, CA, USA)
A high-throughput protein crystallography pipeline for structure-based drug design

12:30 - 12:50
Ditlev Brodersen (Cambridge, UK)
Binding of antibiotics to the 30S ribosomal subunit

12:50 - 15:00 Lunch Break and Poster Session I (Including Mega Posters)

13:30 - 14:40 Perspectives for Structural Genomics in Europe (Room: Dendrite II/III) (Chair: Udo Heinemann)

13:30 - 13:50
Dave Stuart (Oxford, UK)
Structural genomics in Europe: Slow start, strong finish?

13:50 - 14:10
Josefina Enfedaque (European Commission, Brussels)
Structuring European research in structural genomics

14:10 - 14:40
Open discussion

15:00 - 15:40 Plenary Lecture(Chair: Sung-Hou Kim)

Dino Moras (Illkirch, France)
Ligand binding to nuclear hormone receptors

15:40 - 16:20 Biological Insight from Large Sets of Protein Structures (Chair: Sung-Hou Kim)

15:40 - 16:00
Sarah Teichmann (Cambridge, UK)
Domain duplications and combinations in Escherichia coli metabolic enzymes

16:00 - 16:20
Jeff Bonanno (New York, NY, USA)
The GHMP kinase superfamily: Evolutionary and mechanistic implications arising from structural studies

16:20 - 16:50 Coffee Break

16:50 - 17:50 Verified Hypotheses from Protein Structures (Chair: Andrzej Joachimiak)

16:50 - 17:10
Sung-Hou Kim (Berkeley, CA, USA)
Molecular functions of "hypothetical proteins" inferrable by their structures

17:10 - 17:30
Aled Edwards (Toronto, Canada)
Biochemical validation of structural hypotheses

17:30 - 17:50
Hartmut Oschkinat (Berlin, Germany)
Hypotheses about activities and functions of non-catalytic protein domains from NMR investigations

17:50 - 19:10 NMR Methods for Structural Genomics (Chair: Cheryl H. Arrowsmith)

17:50 - 18:10
Miguel Llinás (Pittsburgh, PA, USA)
Is it NMR or is it crystallography? CLOUDS, a direct method for protein structure elucidation via NMR proton densities.

18:10 - 18:30
Gaetano Montelione (Piscataway, NJ, USA)
Automated analysis of protein NMR assignments and structures

18:30 - 18:50
P. Güntert (Yokohama, Japan)
Automated NMR structure calculation with the new software CYANA

18:50 - 19:10
M.A. Kennedy (Richland, WA, USA)
NMR-Based Structural Genomics at the Pacific Northwest National Laboratory, USA

20:00 Speakers' Dinner (by invitation)